課程資訊
課程名稱
專題討論
Seminar 
開課學期
108-2 
授課對象
生化科技研究所  
授課教師
廖憶純 
課號
BST8000 
課程識別碼
B22 D0020 
班次
02 
學分
1.0 
全/半年
半年 
必/選修
必修 
上課時間
星期四8,9(15:30~17:20) 
上課地點
 
備註
必修4學期。上課地點:共同102。與黃楓婷、鄭梅君合授
限博士班
總人數上限:5人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1082BST8000_02 
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課程概述

專題討論二 

課程目標
待補 
課程要求
待補 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
待補 
參考書目
待補 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
  Master Day (系五教室) 
第2週
  李怡萱 Puerarin inhibits inflammation and oxidative stress in dextran sulfate sodium-induced colitis mice model. Biomed Pharmacother. 124:109847 (2020)
黃政睿 Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis. Sci. Adv. 6:eaay9819 (2020) 
第3週
  簡宏廷 miR-21 may Act as a Potential Mediator Between Inflammation and Abnormal Bone Formation in Ankylosing Spondylitis Based on TNF-alpha Concentration-Dependent Manner Through the JAK2/STAT3 Pathway. Dose Response 18:1559325819901239 (2020)
邱筱茹 Beta-Catenin/Tcf7l2-Dependent Transcriptional Regulation of GLUT1 Gene Expression by Zic Family Proteins in Colon Cancer. Sci. Adv. 5:eaax0698 (2019) 
第4週
  賴冠錞 PROTAC induced-BET protein degradation exhibits potent anti-osteosarcoma activity by triggering apoptosis. Cell Death Dis. 10:815 (2019)
鄧家蓉 A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV. J. Virol. 92:18 e00837-18 (2018) 
第5週
  兒童節補假 
第6週
  高先穎 Endometrial Axin2+ Cells Drive Epithelial Homeostasis, Regeneration, and Cancer following Oncogenic Transformation. Cell Stem Cell 26:64-80 (2020)
陳姿吟 The G Protein -Subunit, AGB1, Interacts with FERONIA in RALF1-Regulated Stomatal Movement. Plant Physiol. 176:2426-2440 (2018)
蘇俊熙 PRH1 mediates ARF7-LBD dependent auxin signaling to regulate lateral root development in Arabidopsis thaliana. PLoS Genet. 16:e1008044 (2020) 
第7週
  曾翊翔 Long noncoding RNA AC003092.1 promotes temozolomide chemosensitivity through miR-195/TFPI-2 signaling modulation in glioblastoma. Cell Death Dis 9:1139 (2018)
林欣誼 PERK-mediated expression of peptidylglycine α-amidating monooxygenase supports angiogenesis in glioblastoma. Oncogenesis. 9:18 (2020) 
第8週
  吳冠怡 Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci. Rep. 9, Article number: 19654 (2019)
王子維 Circadian and sleep/wake-dependent variations in tau phosphorylation are driven by temperature. Sleep. pii: zsz266 (2019) 
第9週
  周維謙 Bacterial Outer Membrane Vesicles (OMVs)-based Dual Vaccine for Influenza A H1N1 Virus and MERS-CoV. Vaccines 7:46 (2019)
廖紘陞 Arabidopsis NITROGEN LIMITATION ADAPTATION regulates ORE1 homeostasis during senescence induced by nitrogen deficiency. Nat Plants. 4: 898-903 (2018) 
第10週
  陳琳瑄 PDIA6 regulates insulin secretion by selectively inhibiting the RIDD activity of IRE1. FASEB J. 30: 653-665 (2016)
林頁彤 Using Tetracysteine-Tagged TDP-43 with a Biarsenical Dye To Monitor Real-Time Trafficking in a Cell Model of Amyotrophic Lateral Sclerosis. Biochemistry 58:4086-95 (2019)
尤恩 Insulin–Insulin-like Growth Factors Hybrids as Molecular Probes of Hormone:Receptor Binding Specificity. Biochemistry 55:2903-2913 (2016) 
第11週
  林家伃 ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway. Nat. Cell Biol. 21: 579–591 (2019)
莊佳寶 TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway. Nat Commun. 11:348 (2020) 
第12週
  羅宇茜 IRE1B degrades RNAs encoding proteins that interfere with the induction of autophagy by ER stress in Arabidopsis thaliana. Autophagy. 14:1562-1573 (2018)
吳孟庭 An order-to-disorder structural switch activates the FoxM1 transcription factor. eLife 8:e46131. (2019) 
第13週
  呂湘庭 KDM3A Senses Oxygen Availability to Regulate PGC1α-Mediated Mitochondrial Biogenesis. Mol. Cell 76: 885-895 (2019)
賴宣妤 TOR Signaling Promotes Accumulation of BZR1 to Balance Growth with Carbon Availability in Arabidopsis.
Curr. Biol. 26:1854-1860 (2016) 
第14週
  許嘉珈 Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells. Science 360 (6391): eaan5931 (2018)
張法理 ATP binding cassette transporters ABCG1 and ABCG16 affect reproductive development via auxin signalling in Arabidopsis. Plant J. (2020)
趙伯宣 Intrinsically disordered proteins drive membrane curvature. Nat Commun 6: 7875 (2015) 
第15週
  鄭洛凡 MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer. Br J Cancer (2020). Published date: 16 January 2020
陳沚郁 Targeting lipid metabolism to overcome EMT- associated drug resistance via integrin β3FAK pathway and tumor-associated macrophage polarization using legumain-activatable delivery. Theranostics. 9: 265-278 (2019) 
第16週
  林偉康 Overexpression of microRNA-155 enhances the efficacy of dendritic cell vaccine against breast cancer. Oncoimmunology 9:e1724761 (2020)
陳姿廷 Identification of a Chlorophyll Dephytylase Involved in Chlorophyll Turnover in Arabidopsis. Plant Cell. 28: 2974-2990 (2016) 
第17週
  端午節放假